This web interface and the underlying
SpliceAI server are being developed by the
TGG at the
Broad Institute.
The
SpliceAI server optionally uses pre-computed
scores provided by Illumina for SNVs and small InDels, but resorts to running the
SpliceAI model
directly for scores not available in the pre-computed files - such as larger InDels or non-default "Max distance" values.
NOTE: The API currently only supports interactive use. For automated batch processing, please use the
source code
to set up your own local instance of the API server or just run the underlying SpliceAI tool.
For more information on the SpliceAI model, see
Jaganathan et al, Cell 2019 and
github.com/Illumina/SpliceAI,
as well as in this
recorded talk by Kishore Jaganathan.